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an anal fissure is a break, or tear, in the mucous membrane lining of the anus. The anus is the opening at the end of the digestive tract where stool leaves the body. A fissure is caused primarily by constipation, which leads to straining to pass large hard stools trauma caused by insertion of objec. Anal fissure slitlike separation of anal mucosa that lies below the dentate line. Majority (70 to 80) are in the posterior midline region anterior midline lesions (10 to 20) are more common in women. Mucus is a slimy, slippery fluid that acts as a lubricant and protects various structures in the body. There are a number of mucus-secreting cells in the body, but mucus is most prominent in the respiratory, genital and gastrointestinal tracts, notes the university of colorado at boulder 1. When the gastrointestinal tract becomes infected or undergoes frequent irritation, the mucus-secreting. mucus in the body is natural and a very important part of how the body works. The mucous membrane of the large intestine helps stool to pass. A little mucus is commonly found in the stool and shouldnt be cause for concern. An anal fissure is a small tear or crack in the lining of the anus. If you experience severe pain or bright red bleeding during or after bowel movements, you may have an anal fissure. 1 it is the area between the anal verge and the junction of the stratified cuboidal and columnar epithelium (dentate line). 2 it is lined by squamous epithelium in the lower anal canal below which sebaceous glands and hair follicles arise but changes to stratified cuboidal and, finally. Mucous membrane, membrane lining body cavities and canals that lead to the outside, chiefly the respiratory, digestive, and urogenital tracts.