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Welcome! Discuss your experiences, share your stories and get friendly help and advice. ive been wanting to try topical antibiotics for a while and this post made me go get neosporin. Most anal fissures heal with home treatment after a few days or weeks. If you have an anal fissure that hasnt healed after 8 to 12 weeks, it is considered a long-term (chronic) fissure. I ve had these anal fissures for 4 months now and i ve use all the hydrocortisone hc and analpram hc both of these burn like fire after applying it i tried cowboying up and waiting it out for about hr after applying these cream still burns like fire,,so i stop taking and i am using vitiam e oil and petroleum oil to smooth it. But can i use neosporin i use so many creams in the past 4 months. An acute anal fissure looks like a fresh tear, somewhat like a paper cut. A chronic anal fissure likely has a deeper tear, and may have internal or external fleshy growths. A fissure is considered chronic if it lasts more than eight weeks. best way to cure an anal fissure? - neosporin help anal fissure my daughter is three years old and was suffering from an anal fissure for several months. We went to the doctor and have neosporin, vaseline, bandages and fluids used, as we have said. hello, i have experienced an anal fissure (at least thats what i have been told it is), and i cant seem to get over it. First, id like to start off with describing myself im an 18 year old girl, i eat very healthy (mostly vegetables, fruits, and grain products), i am 50 and weigh about 100 pounds (this is average weight for my height). I dont understand how major surgeries can be performed, but there seems to be no quick cure for an anal fissure. I have used the annusol hc and soaked in warm baths, but to no avail. an anal or a rectal fissure is a small tear, cut, or open sore in the skin around the anus. This problem can affect people belonging to all age groups but is more common in infants and young adults. An anal fissure is a small tear or cut in the wall of the anus 1 2. Signs of an anal fissure include painful bowel movements, blood streaks or mucus on the stool or on toilet tissue, and anal itching 1 2. Anal fissures may happen to anyone but are more common in infants, postpartum women, individuals with crohns disease and older adults.